Keywords : cholangiocarcinoma


Epidemiology of Malignant Extra-Hepatic Biliary Tract Obstruction Detected

Omed H.K Abdulwahab

Iraqi Postgraduate Medical Journal, 2016, Volume 15, Issue 1, Pages 102-106

ABSTRACT:
BACKGROUND:
One of the important causes of obstructive jaundice is malignant tumours.
OBJECTIVE:
The current study was undertaken to describe the epidemiology of malignant extra-hepatic biliary tract obstruction in Sulaimaniyah, Kurdistan Region, Iraq.
Patients & Methods: The study was undertaken at Kurdistan centre for gastroenterology & hepatology in Sulaimaniyah city. Patients attending the centre during the period from 1st January 2008 to 1st January 2013 and diagnosed as having a malignancy using endoscopic retrograde cholangiopancreatography were included in the study. A total of 259 patients were found to have such a malignancy and therefore included.
RESULTS:
The mean age of patients was 63.5 years, the male to female ratio was 1:3 and the most common cause of malignant extra-hepatic biliary tract obstruction was cholangiocarcinoma 47.5%, followed by ampullary and peiampullary carcinoma 26.6%. In males, 37.7% of cancers were cholangiocarcinoma, 30.8% ampullary and periampullary carcinoma, & 26% pancreatic carcinoma, versus 60.2%, 21.2%, & 15% in females respectively (P= 004). Most cancers occurred between 50-79 years of age.
CONCLUSION:
The causes of malignant extra-hepatic biliary obstruction in order of frequency were cholangiocarcinoma, ampullary and periampullary carcinoma, pancreatic carcinoma & carcinoma of the gallbladder.

Management of Choledochal Cysts In Gastroenterology and Hepatology Teaching Hospital

Mohamed H Suadi; Wesam Shakir Hameed; Laith. R. Alhadad

Iraqi Postgraduate Medical Journal, 2012, Volume 11, Issue 4, Pages 516-523

ABSTRACT:
BACKGROUND:
A Choledochal cyst is a rare biliary disease mostly presenting during childhood. Adult presentation is rare and associated diseases and complications are common.
OBJECTIVE:
This study aims to review the management of patients who presented to our hospital with choledochal cysts, focusing on their presentation, preoperative investigations, treatment given and postoperative course.
METHODS:
A prospective and retrospective review of all our choledochal cysts patients from April 2000 to November 2010 was performed
RESULTS:
There were twenty three patients, sixteen females and seven males the average age was 25.82 (range 4-70) years. The commonest presenting complaints were abdominal pain or jaundice. There were eighteen Types I (78.2 %), two of the adult patients had concomitant cholangiocarcinoma (8.6 %), and four patients had cholangitis (two of them had associated cystolithiasis). Fourteen patients treated by total cyst excision with hepaticojejunostomy,
CONCLUSION:
Adult patients with choledochal cysts have associated biliary problems. In view of the high risk of cholangiocarcinoma, early resection and not internal drainage is the appropriate treatment.