Keywords : MRCP
Iraqi Postgraduate Medical Journal,
2018, Volume 17, Issue 2, Pages 157-163
Common bile duct stones may be small or large, single or multiple, the incidence increases with age. Biliary stones present almost always as low signal intensity on MR images. Therefore, the stone is identified as a round or oval- shaped "signal void" within the common bile duct (CBD), surrounded by the high signal intensity bile, CBD stone can present as sharp cutoff of a CBD at the ampulla, often with a well-marginated “meniscus” configuration, CBD stone may be associated with CBD dilatation and/or dilated intrahepatic biliary tree.
To evaluate MRCP signs in detecting CBD stones in patients with obstructive jaundice.
PATIENTS AND METHODS:
The study included 50 patients with jaundice suspecting to have CBD stones as a cause of their complaint ,MRCP parameters include: CBD diameter, meniscus sign ,Status of intrahepatic and extrahepatic ducts, Gall bladder status, Pancreatic duct status Statistical analyses for the results were done.
MRCP diagnose choledocholithiasis in 49(98%) out of 50 patients with a sensitivity of 98%, Accuracy =98%, the specificity of MRCP in diagnosing choledocholithiasis in our study was 95%, P value= 0.001. MRCP show filling defect in 31 patients (3 of them show multiple filling defects) giving Accuracy =62%, sensitivity rate 62%, specificity rate 90%, P value= 0.0001. MRCP show meniscus sign in 18 patients giving Accuracy =36%, sensitivity rate 36%, specificity rate 95%, P value= 0.0001. MRCP show CBD dilatation in 48 patients giving Accuracy =96%, sensitivity rate 96%, specificity rate 95%, P value= 0.001.
MRCP is a non–invasive investigation with high sensitivity, specificity, positive and negative predictive values in detection of CBD stones. Gathering well-defined radiological signs of CBD stones in MRCP allows good diagnostic accuracy. CBD dilatation is the more sensitive sign of detecting CBD stone while meniscus sign is more specific sign for detecting CBD stone in MRCP.
Iraqi Postgraduate Medical Journal,
2007, Volume 6, Issue 1, Pages 7-17
Evaluation of jaundiced patients should include proper history and examination, laboratory investigation and imaging investigations (non invasive like US, CT and MRI or invasive like ERCP and PTC).
AIM OF STUDY:
The aim of this prospective study is to evaluate the role of US and MRI-MRCP in patients with obstructive jaundice in clinical practice.
This is a prospective study performed on 80 patients (42 female and 38 male) with an average age of 53 years presented with obstructive jaundice for whom abdominal ultrasound (US) and magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) performed in the departments of radiology in Al-Kadhemiyyah teaching hospital and Specialized surgical hospital and Baghdad teaching hospital from October 2003 to October 2005. The final diagnosis was found by endoscopic retrograde cholangiopancreatography (ERCP) and or surgery and confirmed by histopathology.
The most common cause of obstructive jaundice in our study was tumors (41.25%) followed by common bile duct stones (36.25%) then benign strictures (13.75%), hydatid cyst (6.25%) & finally choledochal cyst (2.5%). In this study, MRI-MRCP could differentiate surgical from medical jaundice in all cases, while US could differentiate surgical from medical jaundice in 91.25% of cases. MRI-MRCP correctly defines the level of obstruction in all cases (100%).While US correctly define the level of obstruction in only 86.2 % of the total cases. MRI-MRCP correctly suggests the most possible cause of obstruction in 96.25% of cases. While US correctly suggests the most possible cause in only 36.2 %.
So that US, as a screening modality is useful to confirm or exclude biliary dilatation & to choose patients for MRCP examination. MRI-MRCP is a useful non-invasive and essential method in the preoperative evaluation of patients with obstructive jaundice. In addition MRI-MRCP was superior to US or ERCP in studying the extent & staging of malignant lesions