Keywords : Frequency of Occurrence
A Comparative Study of the Frequency of Occurrence of Genetic Skeletal Disorders in Iraq before and after the Second Gulf War, 1991
Iraqi Postgraduate Medical Journal,
2007, Volume 6, Issue 2, Pages 141-146
Genetic skeletal abnormalities are a heterogeneous group of genetic disorders frequently presenting with disproportionate short stature.
AIM OF THE STUDY:
To give an idea about the frequency of genetic skeletal abnormalities, and to find out whether these disorders are really increasing in the last 16 years or not.
During the period extending from (Jan, 1st 2003-April, 1st 2007), all cases of genetic skeletal disorders referred to the Genetic Counseling Clinic, Medical City – Baghdad who were born after 1991 were included in this study as the post-war group; the pre-war group, included all cases of skeletal disorders referred prior to 1991 (Jan., 1st 1987-Jan., 1st 1990). The demographic parameters, family history of the disease plus the parental consanguinity were studied.
The post-war group constituted 3.199% while the pre-war group constituted 2.815%. Both groups had a comparative age range. AR disorders constituted 39.75% of the post-war group and 40% in the pre-war group; AD disorders come next in both groups (37.3% vs. 33.8%) respectively. There is a noticeable increase in the occurrence of new mutations of AD disorders in the post-war group.
Genetic skeletal dysplaisas are not uncommon disorders; their incidence seems to be truly increasing