Keywords : metoclopramide

Comparison of the Effect of Dexamethasone and Metoclopramide in Prevention of Post-Operative Nausea and Vomiting in Laparoscopic Cholecystectomy

Iyad Abbas Salman; Redha Mohamed Abdul Hussien Alkabee

Iraqi Postgraduate Medical Journal, 2013, Volume 12, Issue 3, Pages 443-448

Postoperative Nausea and vomiting is Common complication depending on the type of surgery,
technique and duration of anesthesia.
To evaluate the effect of Dexamethasone as antiemetic in comparison with Metoclopramide.
Is aprospective study carried on (100) patients undergone elective cholecystectomy in a period
from Jan. 2009 to April. 2010 in Baghdad Teaching Hospital / Medical city/Baghdad/Iraq.
The patients were allocated into two groups of 50 patients each. Group A received 8mg
Dexamethasone, group B received 10mg metoclopramide intravenously, both groups monitored
postoperatively for nausea and vomitting for 24 hours every 4 hours.
Regarding Nausea, for 24 hrs the results were not significant except at 24th hr., in which nausea
more significant in metoclopramide group.
Regarding Vomiting, there was no significant from postoperative period to 12hr, while from 16 hr.
to 24 hr. there were significant fewer incidences in dexamethasone group.
A single dose of Dexamethasone is effective same as Metoclopramide in prevention of PONV ,
and it is better in late prevention postoperativel