Keywords : KEY WORLDS


The Relationship of Post-Stroke Aphasia Types with Age, Sex and Stroke Type in a Group of Iraqi Patients

Israa Farhan Salman; Akram M; Hasan A. Al-Hamadani; Al-Mahdawi

Iraqi Postgraduate Medical Journal, 2018, Volume 17, Issue 2, Pages 175-182

ABSTRACT:
BACKGROUND :
Aphasia is a condition of Loss or impairment of the production or comprehension of spoken or written language because of an acquired lesion of the brain. Aphasia is most often caused by stroke.
OBJECTIVE:
To assess the relationship of post-stroke aphasia types with age, sex and stroke types
PATIENTS AND METHODS:
A hospital - based cross sectional survey study conducted at Baghdad teaching hospital and Al Imamain Al kadhmain medical city between October 2014 and September 2015. One hundred patients with different types of patients with proved diagnosis of stroke by clinical and radiological assessment in young age group and old one of both genders and both left and right handed were included. Data regarding the clinical and demographic characteristics of the patients were reported including: Age, gender, handedness, stroke types, stroke side, stroke site, and aphasia types.
RESULTS:
A total of 100 patients with different types of stroke were enrolled in this study. The mean age of the studied group was 62.1 ± 13.2 (range: 37-87) years, moreover, majority of the studied group aged more than 50 years. Females were relatively the dominant than males; 55 (55%) vs. 45 (45%) respectively. Ischemic stroke was the dominant type of stroke among cases it was reported in 76 cases (76%) compared to only 24 (24%) of hemorrhagic type. Global aphasia was found in 32 stroke cases (32%), Broca´s in 17 (17%), Thalamic 17 (17%), Putaminal 11 (11%), Werneck's 11 (11%), Motor transcortical 6 (6%), Conductive and anomia 4 (4%) and the Mixed transcortical in only two cases (2%)
CONCLUSION:
Post stroke Aphasia was more frequent among stroke patients older than 50 years. Ischemic stroke was the dominant type of stroke. Global aphasia was the dominant subtypes of aphasia among the studied group followed by Broca’s. Thalamic and the other subtypes were less frequent.

The Potential Effect of Lipid Profile on Deep Seated Versus Lobar Intracerebral Hemorrhage

Saif M. Tawfeeq; Munther Taher Hamzah; Hasan Azeez Al-Hamadani

Iraqi Postgraduate Medical Journal, 2017, Volume 16, Issue 1, Pages 57-63

ABSTRACT:
BACKGROUND:
Brain hemorrhage is defined as the extravasation of blood from the vascular bed into the intracranial space, resulting in clinical dysfunction of nervous system. Intracerebral hemorrhage is a heterogeneous disease with deep and lobar subtypes. The amount of serum lipid may also affect the integrity of blood vessel wall and abnormal lipid profile may consider as a risk factor for intracerebral hemorrhage.
OBJECTIVE:
The present study was designed to evaluate the relationship between serum lipids and the site of intracerebral hemorrhage.
METHOD:
A cross-sectional study for 100 patients (50 with deep seated, 50 with lobar intracerebral hemorrhage) from Al-Kadhymia teaching hospital and Bagdad Teaching Hospital between August 2012 and June 2014. Case subjects included those patients from 20 to 89 years of age experiencing ICH within first 48 hours of presentation. Total cholesterol (TC), High-density lipoprotein (HDL) cholesterol, Low-density lipoprotein (LDL) cholesterol and Triglycerides (TG) serum level, was compared in deep seated and lobar intracerebral hemorrhage.
RESULTS:
There was significant relationship between high HDL level in deep seated compared to lobar hemorrhage, while there was no statistical significant relationship between the site of hemorrhage by TC, LDL and TG level
CONCLUSION:
High HDL level is a risk factor for deep seated rather for lobar intracerebral hemorrhage.TC, TG, LDL have no effect on the site of hemorrhage.

The Role of Gender in Early Onset Relapsing Remitting Multiple Sclerosis

Hasan Azeez Al-Hamadani

Iraqi Postgraduate Medical Journal, 2015, Volume 14, Issue 2, Pages 250-257

ABSTRACT:
BACKGROUND:
Multiple sclerosis is an autoimmune inflammatory demyelinating disorder of the central nervous system. Multiple sclerosis is now universally found to be more prevalent in women than men
OBJECTIVE:
The aim of the study is to clarify the role of gender in early onset multiple sclerosis
PATIENTS AND METHODS:
This retrospective study was conducted in the multiple sclerosis clinic archive system in the Medical City Hospital in Baghdad, Iraq. Data collection was carried out between March 2008 and March 2009. The patients diagnosed to have relapse remitting multiple sclerosis according to the revised McDonald’s diagnostic criteria for multiple sclerosis, and onset of disease must be before the eighteenth birthday. For each patient, the following information was gathered: age, gender, date of onset, and date of second attack, presenting symptom, and extended disability status scale and the date, and type and location of MRI lesions. A p-value <0.05 was considered the cutoff point to determine significant findings.
RESULTS:
Forty-eight of the patients where females (62.3%) and 29 patients where males (37.7%), with a female: male ratio 1.6:1.
No significant difference was found regarding distribution of gender in each age group, and no significant difference was found when age at onset was compared between males and females, although in male patients a shift to children and a shift at adolescence in female were observed
The comparison of different radiological sites between males and females shows a significant difference with more males having infratentorial lesions compared with females (P=0.033).
No significant difference was found between the two genders regarding, age at onset the presenting symptom, mode of onset and no significant difference was found when interval between the first and second attack was compared between males and females.
CONCLUSION:
Female preponderance was highest for subjects with disease onset at adolescents. No significant difference was found when age at onset was compared between males and females, although in male patients, a shift to children and a shift at adolescence in female were observed. A significant difference in the time, between first and second attack between males and females. A significant difference in the MRI findings was the finding that males had a higher incidence of infratentorial lesion than females.