Keywords : containing herbs


Effects of Herbs – Containing Phytoestrogens on Rat Testis: A Histological, Histochemical and Biochemical Study

Malak A. Al-Yawer

Iraqi Postgraduate Medical Journal, 2011, Volume 10, Issue 4, Pages 562-572

ABSTRACT:
BACKGROUND:
Estrogens has traditionally been known as the female hormone, but this idea has been challenged in early 1990’s and an essential physiological role for estrogen in male fertility was identified. Phytoestrogens are naturally occurring non-steroidal plant chemicals that can act like the female hormone estrogen. The herbs ( anise alfalfa and vervain ) chosen in this study contain phytoestrogens.
OBJECTIVE:
Previous studies demonstrated controversy of the effects of phytoestrogens on the rat testes .Hence, the present investigation was undertaken to investigate the influence of typical dose of herbs containing phytoestrogen on the rat testis.
MATERIALS AND METHODS:
Twenty-four apparently normal mature male rats were divided into four groups of 6 animals each. The first "control" group received only 4ml of distilled water as a placebo. The second group received 40mg/kg of anise seed; the third group received 53.3 mg/kg of dried herb of vervain and the fourth group received 400 mg /kg of alfalfa seeds. All experimental groups received the doses through oro-gastric tube daily for fourteen days. Testicular histology was evaluated by light and enzyme histochemistry. Plasma FSH and testosterone concentrations were taken to support our results.
RESULTS:
Histological examination of anise, alfalfa and vervain – treated groups showed an increase in the height of germinal epithelia. There was marked lipoprotein lipase activity in the whole of the interstitial tissue which is more in amount in experimental groups than that in control group. Acid phosphatase granules were infiltered the seminiferous epithelia mildly in control group , moderately in anise and vervain groups and markedly in alfalfa group. The number of interstitial cells showing marked acid phosphatase activity was higher in all experimental groups than that in control group. Alkaline phosphatase exhibited intense activity in the boundary tissue of the seminiferous tubules in testes of control and experimental groups but it appeared thicker in the latter.
CONCLUSION:
The low dose and short duration of treatment used in our study made these phytoestrogen – containing herbs to have a stimulatory effect on leydig cell steroidogenesis. This study also demonstrated that aniseed being the most potent of the three herbs followed by alfalfa in stimulating testosterone synthesis. This is possibly attributed to the coumarin constituent of aniseed and alfalfa.

Correlation of Angiographic Findings and Clinical Presentations in Unstable Angina

Ali Abdulamir Mohammad AL.Mossawi; Kasim Abbas Ismail; Azher Sabih Zubaidy; Adil Siwan Aqabi; Majid Hameed AL Maini; Jawad K. Mnuti; Fadhil A. AL- Abbudi; Amira H. Shubbar; Layth Rafea Taqa; Sawsan Sati; Abbas; Najat Abul; Razak; Noor Mustafa; Razeqa Abd Ali; Nassir Enssief Mohsun; Raji H AL-Hadithi; Suhaila Saadallah; Darya Akram Faqe Mahmood; Ari R. Qader; Kurdo A. Mohmmad; Dawood Salman Hameed Alazzawi; s Central Teaching Hospital in Baghdad; a Descreptive Study; Autism Among Children Attending Pediatric Psychiatric Department in Child; Jaafar Muhamed Hassan; AL- Ghabban; Haider Abdul Muhsin; Huda Adnan Habib; Maysaloun Muhammed Abdulla; Selwa Elias Yacoub; Abdulrazak H. Alnakash; Shaema Jafar; Yousef Abdul-Raheem; Alaa Hussein Ali; Montadhar Hameed Nima; Rasha Abbas Azeez; Jassim Mohammad Alkhazraji; Hussein Mahmood Gazi; Mohammed Shafik Tawfeek; Nabeel Ghazi Hashim; Hayder Hadi Lazim; Maysoon Mohammad Najeeb Mohammad Saleem; Arieg Abdul Wahab Mohammad; Majid Syki Jabir; Kareem Al-Tameemi; Malak A. Al-Yawer; Adel Rabea Alsaadawi; Mohammed S. Saeed; Thukaa T. Yahya; Osama E. Hudder; Issraa A. Hussein

Iraqi Postgraduate Medical Journal, 2011, Volume 10, Issue 4, Pages 449-455

ABSTRACT: BACKGROUND: Unstable angina is usually related to acute thrombosis superimposed on a disrupted plaque. The highest; level of Braunwald classification of unstable angina can be used to assess the severity of clinical presentation. However the highest classes have not been directly correlated with thrombotic and complex lesions. OBJECTIVE: The study was done to clarify the correlation between angiographic findings and the most acute and / or severe clinical presentation in unstable angina. PATIENTS AND METHOD: We conducted a prospective study of 110 patients of unstable angina at Ibn-Albitar Center for Cardiac Surgery. All of these patients underwent cardiac catheterization, culprit lesion was identified in 80 patients and in 30 patients there was no an identifiable culprit lesion .Complex lesions including complex morphology, intracoronary thrombus, or total occlusion were also quantitatively analyzed and Thrombolysis in Myocardial Infarction (TIMI) flow grade was assessed. Patients were classified according to Braunwald classification in instable angina .We compared patients with and those with no culprit lesions in regarding Braunwald classification. We sequentially compared the highest Braunwald classes II, C, 3 with classes

Keywords

braunwald classification
---
unstable angina

Correlation of Angiographic Findings and Clinical Presentations in Unstable Angina

Ali Abdulamir Mohammad AL.Mossawi; Kasim Abbas Ismail; Majid Hameed AL Maini; Adil Siwan Aqabi; Azher Sabih Zubaidy; Jawad K. mnuti; Fadhil A. AL- Abbudi; Amira H. Shubbar; DEFINITION GERD is described as any symptomatic or histopathological alteration resulting from episodes of gastroesophageal reflux; Layth Rafea Taqa; INTRODUCTION; Reflux esophagitis describes the subset of GERD patient with histopathological changes of; Sawsan Sati; Najat Abul; Razak; Noor Mustafa; Razeqa Abd Ali; Suhaila Saadallah; Raji H AL-Hadithi; Darya Akram Faqe Mahmood; Ari R. Qader; Kurdo A. Mohmmad; Dawood Salman Hameed Alazzawi; Entissar Hadi AL- Shimery; Jaafar Muhamed Hassan; AL- Ghabban; Haider Abdul Muhsin; Huda Adnan Habib; Maysaloun Muhammed Abdulla; Selwa Elias Yacoub; Abdulrazak H. Alnakash; Shaema Jafar; Yousef Abdul-Raheem; Alaa Hussein Ali; Montadhar Hameed Nima; Rasha Abbas Azeez; Jassim Mohammad Alkhazraji; Hussein Mahmood Gazi; Mohammed Shafik Tawfeek; Nabeel Ghazi Hashim; Hayder Hadi Lazim; Maysoon Mohammad Najeeb Mohammad Saleem; Arieg Abdul Wahab Mohammad; Majid Syki Jabir; Kareem Al-Tameemi; Malak A. Al-Yawer; Adel Rabea Alsaadawi; ABSTRACT; Issraa A. Hussein; Osama E. Hudder; Thukaa T. Yahya

Iraqi Postgraduate Medical Journal, 2010, Volume 9, Issue 4, Pages 449-455

ABSTRACT:
BACKGROUND:
Unstable angina is usually related to acute thrombosis superimposed on a disrupted plaque. The highest;
level of Braunwald classification of unstable angina can be used to assess the severity of clinical
presentation. However the highest classes have not been directly correlated with thrombotic and complex
lesions.
OBJECTIVE:
The study was done to clarify the correlation between angiographic findings and the most acute and / or
severe clinical presentation in unstable angina.
PATIENTS AND METHOD:
We conducted a prospective study of 110 patients of unstable angina at Ibn-Albitar Center for Cardiac
Surgery. All of these patients underwent cardiac catheterization, culprit lesion was identified in 80
patients and in 30 patients there was no an identifiable culprit lesion .Complex lesions including complex
morphology, intracoronary thrombus, or total occlusion were also quantitatively analyzed and
Thrombolysis in Myocardial Infarction (TIMI) flow grade was assessed. Patients were classified
according to Braunwald classification in instable angina .We compared patients with and those with no
culprit lesions in regarding Braunwald classification. We sequentially compared the highest Braunwald
classes II, C, 3 with classes

Keywords

braunwald classification
---
unstable angina

Effects of Herbs – Containing Phytoestrogens on Rat Testis: A Histological, Histochemical and Biochemical Study

Malak A. Al-Yawer

Iraqi Postgraduate Medical Journal, 2010, Volume 9, Issue 4, Pages 562-572

ABSTRACT:
BACKGROUND:
Estrogens has traditionally been known as the female hormone, but this idea has been challenged in
early 1990’s and an essential physiological role for estrogen in male fertility was identified.
Phytoestrogens are naturally occurring non-steroidal plant chemicals that can act like the female
hormone estrogen. The herbs ( anise alfalfa and vervain ) chosen in this study contain
phytoestrogens.
OBJECTIVE:
Previous studies demonstrated controversy of the effects of phytoestrogens on the rat testes .Hence,
the present investigation was undertaken to investigate the influence of typical dose of herbs containing
phytoestrogen on the rat testis.
MATERIALS AND METHODS:
Twenty-four apparently normal mature male rats were divided into four groups of 6 animals each. The
first "control" group received only 4ml of distilled water as a placebo. The second group received
40mg/kg of anise seed; the third group received 53.3 mg/kg of dried herb of vervain and the fourth
group received 400 mg /kg of alfalfa seeds. All experimental groups received the doses through orogastric
tube daily for fourteen days. Testicular histology was evaluated by light and enzyme
histochemistry. Plasma FSH and testosterone concentrations were taken to support our results.
RESULTS:
Histological examination of anise, alfalfa and vervain – treated groups showed an increase in the height
of germinal epithelia. There was marked lipoprotein lipase activity in the whole of the interstitial tissue
which is more in amount in experimental groups than that in control group. Acid phosphatase granules
were infiltered the seminiferous epithelia mildly in control group , moderately in anise and vervain
groups and markedly in alfalfa group. The number of interstitial cells showing marked acid
phosphatase activity was higher in all experimental groups than that in control group. Alkaline
phosphatase exhibited intense activity in the boundary tissue of the seminiferous tubules in testes of
control and experimental groups but it appeared thicker in the latter.
CONCLUSION:
The low dose and short duration of treatment used in our study made these phytoestrogen – containing
herbs to have a stimulatory effect on leydig cell steroidogenesis. This study also demonstrated that
aniseed being the most potent of the three herbs followed by alfalfa in stimulating testosterone
synthesis. This is possibly attributed to the coumarin constituent of aniseed and alfalfa