Prognostic Indicators in Patients with Relapsing Remitting Multiple Sclerosis
Iraqi Postgraduate Medical Journal,
2015, Volume 14, Issue 3, Pages 403-409
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system affecting nearly 2 million people worldwide. Multiple sclerosis typically begins in early adulthood and has a variable prognosis.
To determine the factors that affects the prognosis in Iraqi patients with relapsing remitting multiple sclerosis.
PATIENTS AND METHODS:
This study includes fifty patients with relapsing remitting MS and was conducted from March 2007 to July 2008 in Baghdad Teaching Hospital MS clinic. A study protocol sheet was done and filled from the patient’s database in the MS clinic. The prognostic indicator of residual disability depends on the Expanded Disability Status Scale (EDSS).
The mean age for the study sample was 45.58 years, with 27 male and 23 female. High percentage of patients presented as monosymptomatic (70%), most of the symptoms was spinal (48%). The mean value for relapses was 2.3 with maximum number of 6. The study shows that there is no significant effect of gender as a prognostic indicator on the residual disability of patient with relapsing remitting MS. There is significant correlation between the age at CDMS and the EDSS in the first visit (EDSS1).
We concluded that the older age at onset, pyramidal and sphincteric involvement at the beginning of the illness and more relapses in the first 2 years of the illness all are associated with poor prognosis.
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