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Effect of Midazolam on Heart Rate in Pediatric Anesthesia

    Sanaa Fareed Qassim

Iraqi Postgraduate Medical Journal, 2016, Volume 15, Issue 4, Pages 441-445

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Abstract

ABSTRACT:
BACKGROUND :
Midazolam is one of benzodiazepines. It is most lipid soluble as a result has a rapid onset and short duration of action, used in anesthesia for sedation or intravenous induction according to the dose used.
OBJECTIVE:
Is to notice if there is an effect of midazolam on heart rate in pediatric patients with using ketamine as induction agent under general anesthesia.
PATIENTS AND METHODS:
60 peadiatric patients undergoing surgery randomly allocated in 2 groups(A and B). Aneasthesia was standardized for all patients (except addition of Midazolam in sedative dose (0.03 mg/kg) i.v. preinduction to group( B). Heart rate measured preoperatively as abaseline and 5 and 15 minutes after induction.
RESULTS:
Adding midazolam associated with a reduction in HR by an average of 10 beats/min 5 and 15 minutes after induction of anaesthesia. This effect failed to reach the level of statistical significance although it was clinically significant.
CONCLUSION:
Midazolam have well known sedative effect but have no significant effect on heart rate in paediatric patients.
Keywords:
    KEYWORDS heart rate ketamine
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(2016). Effect of Midazolam on Heart Rate in Pediatric Anesthesia. Iraqi Postgraduate Medical Journal, 15(4), 441-445.
Sanaa Fareed Qassim. "Effect of Midazolam on Heart Rate in Pediatric Anesthesia". Iraqi Postgraduate Medical Journal, 15, 4, 2016, 441-445.
(2016). 'Effect of Midazolam on Heart Rate in Pediatric Anesthesia', Iraqi Postgraduate Medical Journal, 15(4), pp. 441-445.
Effect of Midazolam on Heart Rate in Pediatric Anesthesia. Iraqi Postgraduate Medical Journal, 2016; 15(4): 441-445.
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