Uremic Pruritus in Haemodialysis Patients; Prevalence, Severity and Possible Associations
Iraqi Postgraduate Medical Journal,
2015, Volume 14, Issue 4, Pages 548-554
Uremic pruritus is a common distressing complication of end stage renal disease and it is a common problem in dialysis patients. It causes serious discomfort and skin damage, negatively affects the quality of life.
To determine the prevalence, severity of pruritus and possible association with the laboratory parameters in patients with chronic renal disease on haemodialysis.
One hundred and three patients on chronic haemodialysis were included in this study. Fasting blood sugar, urea, creatinine, albumin, alkaline phosphatase, parathyroid hormone, sodium, potassium, chloride, calcium, phosphorus, calcium × phosphorus product, were determined.
Of the 103 patients included in the study the, 79 patients (76.7%) had pruritus of whom, 27 (34.1%) had mild pruritus, 30 (37.9%) had moderate and 22 (27.8%) had severe pruritus. No significant association (p ˃ 0.05) was found between pruritus and each of sex, age, frequency and duration of haemodialysis. There was a significant association (p ˂ 0.05) between duration of haemodialysis and pruritus onset. No significant difference (p ˃ 0.05) in the FBS, urea, creatinine, albumin, parathyroid hormone, alkaline phosphatase, sodium, potassium, chloride, calcium, phosphorus, calcium phosphorus product, average among patients who had no pruritus, mild, moderate and severe pruritus. A significant positive correlation (p ˂ 0.05) was found between severity of pruritus in pruritic patients and age.
WE CONCLUDED THAT there was a significant association between duration of haemodialysis and pruritus onset more over the age had a significant positive correlation with the severity of pruritus in pruritic patients.
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