Outcome of Hemolytic Uremic Syndrome in Iraqi Children a Single Centre Experience in Baghdad
Iraqi Postgraduate Medical Journal,
2019, Volume 18, Issue 2, Pages 182-187
Hemolytic uremic syndrome (HUS) is important cause of acute kidney injury (AKI) and chronic kidney disease (CKD) in children. Proposed prognostic features are controversial.
Our objective was to study the characteristics of HUS and determine short-term outcome and risk factors for prognosis in children followed in a single center in Baghdad city.
PATIENTS AND METHODS:
We reviewed, retrospectively, the records of children with HUS seen at child welfare Teaching hospital, Baghdad( April2015- April 2017and studied outcome and some prognostic risk factors.
Thirty-three children with HUS were recorded; 40% had diarrhoea positive (D+) and 60% diarrhoea negative (D−) HUS. The mean age was 47.8 40.4 months and males were 63.6%. At the acute phase seizures and hypertension were present in 33.5%, and 66.7% respectively. Severe anaemia, thrombocytopenia, and leukocytosis were present in 87.9%, 96.6%, and 27.2% respectively. Clinical and laboratory features were not significantly different in D+ and D− cases (P > 0.05 for all parameters). Dialysis was undertaken forall patients. Demographic, clinical and laboratory features were not significant risk factors for adverseoutcome. At short-term follow up (mean period ± SD of 18.54 ± 13.21 months), 42.2% had complete renal recovery, 35.4chronic kidney disease, and 24.2% died.
In spite of institution of dialysisand supportive therapy for all patients, our data showed less favorable outcome of HUS.
KEYWORDS: Children, Hemolytic uremic syndrome, Outcome
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