Association of Helicobacter Pylori and Nasal Polyposis
Iraqi Postgraduate Medical Journal,
2012, Volume 11, Issue 1, Pages 92-96
Helicobacter pylori is recognized as an important human pathogen by virtue of its association with
peptic ulcer disease , gastric cancer , gastric lymphoma and high prevalence of infection
worldwide. Recently this organism was detected in tonsil and adenoid tissue after
adenotonsillectomy , as well as in mucosa of patients with chronic rhinosinusitis , but its
association with simple nasal polyposis has not been investigated yet in our country .
To investigate a possible contribution of Helicobacter pylori (H.pylori) in the etiopathogenesis of
simple nasal polyps .
Study Design: Prospective clinico –pathological investigation.
Twenty eight patients with nasal polyposis were studied for the presence of Helicobacter pylori in
the nasal polyp specimens by histopathological examination of serial sections stained by modified
Giemsa stain .
Helicobacter pylori was detected in 10 (35%) of total 28 simple nasal polyps specimens.
This study found a significant percentage 10/28 patients (35%) with Helicobacter pylori infection
in nasal polyps and to confirm the role of Helicobacter pylori in the etiopathogenesis of nasal
polyposis , extensive epidemiological studies would be necessary
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