Spectroscopic Studies of the Purified Testosterone Receptors in Human Benign and Malignant Prostatic Tumors
Iraqi Postgraduate Medical Journal,
2007, Volume 6, Issue 4, Pages 320-332
To study the human benign and malignant prostatic testosterone receptors spectroscopically in the UV region.
MATERIALS AND METHODS:
In this study, spectroscopic characterization in the UV region was carried out on purified testosterone receptors by determining the polarity and pH effects on receptor UV spectra. Spectrophotometric pH titration and the observation of the thermal stability of testosterone receptors were also included in the present study.
The UV spectra of purified testosterone receptors separated from benign prostatic tumors. BI receptor has two peaks at 196nm and 256.4nm, BII purified receptor gives one peak at 195.5nm, MI purified receptor gives one peak at 194nm and MII purified receptor gives one peak at 193.1nm.
This study provides useful information about the spectroscopic characterization of testosterone receptors isolated from two types of human prostatic tumors.
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