Factors Affecting Intra-Cytoplasm Sperm Injection (ICSI) and Pregnancy Outcome in the Fertility Center of Al – Najaf City
Iraqi Postgraduate Medical Journal,
2013, Volume 12, Issue 0, Pages 706-711
Knowing predictors of pregnancy in IVF is helpful for clinicians to individualize the treatment plans and improve patient counseling and for patients to decide whether to undergo infertility treatment.
A prospective and retrospective study to determine the factors affecting results and outcome of Intra-Cytoplasm Sperm Injection (ICSI) ICSI in the treatment of sub-fertile patients and the pregnancy outcome.
PATIENTS AND METHODS:
140 couples underwent IVF cycle in the form of intra-cytoplasm sperm injection ICSI enrolled in the study, pregnancy rate was analyzed according to the age, type, cause and duration of sub-fertility, hormonal assay, endometrial thickness, type of treatment protocol, number of retrieved oocytes, number of embryos transferred and sperm parameter.
From the total of 140 women, 23 (16.43%) were cancelled, among 117 cycle, the pregnancy rate was 25.27%, fertilization rate was 39.87%. Factors which significantly affect the outcome of ICSI included the age of the women as fertility decline with advanced age, type and causes of sub-fertility. Sperm quality was more important than sperm number, and the number of embryos transferred also affect pregnancy outcome.
Multiple factors affecting ICSI outcome, the most important one is female age, The cause and type of sub-fertility also affect the outcome.
KEY WORDS: intracytoplasm-sperm injection (ICSI)
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