Comprative Study between LAT and Elisa in Detection of Toxoplasmosis in Groups of Women
Iraqi Postgraduate Medical Journal,
2014, Volume 13, Issue 1, Pages 51-54
Toxoplasmosis is a zoonotic disease caused by the parasitic protozoan Toxoplasma gondii . This parasite is an obligate intracellular organism and is found in two forms in humans. widespread throughout the world, approximately half a billion humans have antibody to T. gondii.
This study aimed to compare the efficiency of two methods in diagnosis of toxoplasmposis in pregnant and non-pregnant women.
Blood samples were collected from 350 (15-46 year-old, 100 pregnant and 250 non-pregnant) females. Two serological methods were used: Latex agglutination test (LAT) and Enzyme linked immune-sorbent assay for IgM detection (ELISA).
The study showed that 38.86% of women had given positive results for LAT, of which 31 were pregnant and 105 were non-pregnant, while only 14.28% of the total subjects had given positive results for ELISA.
These results indicate that positive sera for LAT should be further investigate by more reliable method in order to confirm the infection with toxoplasmosis.
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