Relationship Between Tei index and Left Ventricular Geometric Patterns in Hypertensive Patients
Iraqi Postgraduate Medical Journal,
2014, Volume 13, Issue 1, Pages 70-74
Various left ventricular geometric patterns occur in hypertension and may affect the cardiovascular risk profile of hypertensive subjects. Tei index is a combined index of systolic and diastolic functions and has been shown to be a predictor of cardiovascular outcome in heart diseases.
The aim of this study was to investigate the relationship between Tei index and left ventricular (LV) geometry in hypertensive patients.
Two dimensional-guided M-mode echocardiography and Doppler study were performed in 122 hypertensive patients and 67 control subjects. This study was conducted at Baghdad Medical City / Teaching Hospital and Alshahed Mohammed B. Alhakem Hospital in Alshulla city . According to the value of relative wall thickness (RWT) and left ventricular mass index (LVMI), hypertensive patients were subdivided into four geometric patterns. The Tei index was obtained from the summation of isovolumic relaxation time (IVRT) and isovolumic contraction time (IVCT), divided by the ejection time. Statistical analysis was done using SPSS 17.0.
This study showed that the Tei index was significantly higher among the hypertensive patients with concentric hypertrophy(CH), eccentric hypertrophy(EH), concentric remodeling and normal geometry compared with the control group(0.81±1.1, 0.78±0.3, 0.69±0.3, 0.59±0.5 respectively). Tei index was correlated to the left ventricular ejection fraction (LVEF), left ventricular fractional shortening(LVFS), mitral E/A ratio, heart rate(HR), LVMI and RWT.
The Tei index are impaired in all subgroups of hypertensive patients according to their LV geometry compared to control group. This impairment is more advanced in patients with concentric and eccentric hypertrophy.
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